Batch-Applying Presets using Lightroom

Photofocus (old site)

For those of you who use Lightroom, you are probably familiar with Develop presets and how to use them. However, something that has baffled me for quite some time is how to batch-apply a preset to a large group of photographs. The most common answer is always to process one photograph (or apply a preset to it) and then use the “Sync Settings” feature to sync your image together. That method has always felt laborious, especially when I’m using a preset and I’m not 100% certain what the settings are that I should sync, particularly with images where I do not want to sync all of the settings (such as exposure or white balance).

I am happy to say that I have finally found a way, and it is so easy that I’m almost embarrassed to admit that I didn’t figure this out earlier … just use the Quick Develop…

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Scientists Find Treatment to Kill Every Kind of Cancer Tumor

Scientists Find Treatment to Kill Every Kind of Cancer Tumor

Researchers might have found the Holy Grail in the war against cancer, a miracle drug that has killed every kind of cancer tumor it has come in contact with, the New York Post reported.

The drug works by blocking a protein called CD47 that is essentially a “do not eat” signal to the body’s immune system, according to Science Magazine.

A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted into mice, researchers have found. The treatment, an antibody that blocks a “do not eat” signal normally displayed on tumor cells, coaxes the immune system to destroy the cancer cells.

A decade ago, biologist Irving Weissman of the Stanford University School of Medicine in Palo Alto, California, discovered that leukemia cells produce higher levels of a protein called CD47 than do healthy cells. CD47, he and other scientists found, is also displayed on healthy blood cells; it’s a marker that blocks the immune system from destroying them as they circulate. Cancers take advantage of this flag to trick the immune system into ignoring them. In the past few years, Weissman’s lab showed that blocking CD47 with an antibody cured some cases of lymphomas and leukemias in mice by stimulating the immune system to recognize the cancer cells as invaders. Now, he and colleagues have shown that the CD47-blocking antibody may have a far wider impact than just blood cancers.

“What we’ve shown is that CD47 isn’t just important on leukemias and lymphomas,” says Weissman. “It’s on every single human primary tumor that we tested.” Moreover, Weissman’s lab found that cancer cells always had higher levels of CD47 than did healthy cells. How much CD47 a tumor made could predict the survival odds of a patient.

To determine whether blocking CD47 was beneficial, the scientists exposed tumor cells to macrophages, a type of immune cell, and anti-CD47 molecules in petri dishes. Without the drug, the macrophages ignored the cancerous cells. But when the anti-CD47 was present, the macrophages engulfed and destroyed cancer cells from all tumor types.

Next, the team transplanted human tumors into the feet of mice, where tumors can be easily monitored. When they treated the rodents with anti-CD47, the tumors shrank and did not spread to the rest of the body. In mice given human bladder cancer tumors, for example, 10 of 10 untreated mice had cancer that spread to their lymph nodes. Only one of 10 mice treated with anti-CD47 had a lymph node with signs of cancer. Moreover, the implanted tumor often got smaller after treatment—colon cancers transplanted into the mice shrank to less than one-third of their original size, on average. And in five mice with breast cancer tumors, anti-CD47 eliminated all signs of the cancer cells, and the animals remained cancer-free 4 months after the treatment stopped.

“We showed that even after the tumor has taken hold, the antibody can either cure the tumor or slow its growth and prevent metastasis,” says Weissman.

Although macrophages also attacked blood cells expressing CD47 when mice were given the antibody, the researchers found that the decrease in blood cells was short-lived; the animals turned up production of new blood cells to replace those they lost from the treatment, the team reports online today in the Proceedings of the National Academy of Sciences.

Cancer researcher Tyler Jacks of the Massachusetts Institute of Technology in Cambridge says that although the new study is promising, more research is needed to see whether the results hold true in humans. “The microenvironment of a real tumor is quite a bit more complicated than the microenvironment of a transplanted tumor,” he notes, “and it’s possible that a real tumor has additional immune suppressing effects.”

Another important question, Jacks says, is how CD47 antibodies would complement existing treatments. “In what ways might they work together and in what ways might they be antagonistic?” Using anti-CD47 in addition to chemotherapy, for example, could be counterproductive if the stress from chemotherapy causes normal cells to produce more CD47 than usual.

Weissman’s team has received a $20 million grant from the California Institute for Regenerative Medicine to move the findings from mouse studies to human safety tests. “We have enough data already,” says Weissman, “that I can say I’m confident that this will move to phase I human trials.”
For the last year, many people have been working to make clinical trials possible. We are now hopeful that the first human clinical trials of anti-CD47 antibody will take place at Stanford in mid-2014, if all goes well. Clinical trials may also be done in the United Kingdom.

 

Link :

http://news.sciencemag.org/health/2012/03/one-drug-shrink-all-tumors?ref=hp

Link:

 

http://stemcell.stanford.edu/CD47/

Green Smoothie

Green Smoothie

Image

Inflammation has a wide range of causes, and is often disguised as anything from weight gain to skin problems, headaches to depression.

Here’s a green smoothie recipe that’s packed with nutrients and ingredients that have anti-inflammatory effects in the body. For a little more substance, try adding in a plant based or brown rice all natural protein powder.

Ingredients

  • 1 cup frozen or fresh pineapple chunks
  • 1 handful of arugula
  • 1 handful of spinach and kale
  • 1/2 inch fresh ginger root, peeled
  • 1 1/2 cups of coconut water and/or green tea
  • 1/2 tsp. of ground turmeric powder or 1/2 inch fresh turmeric root
  • 1/2 tsp. ground cinnamon
  • *optional scoop vegan and gluten-free protein powder
  • water and ice to blend.

Directions

Blend ingredients. Top it with chia seeds and a handful of walnuts. Enjoy!

Understanding Buddhism

lijiun

A lot of people misunderstanding on Buddhism, they associated Buddhism with “Superstitious”.

They thought Buddhists are praying to a statue with fruits, water, flower, Incense, light/lamp and others.

This is NOT TRUE.

There is a meaning behind Buddhist devotional practice.

Once you understand more on Buddhism, you’ll know it’s scientific, nothing link with “Superstitious”.

BUDDHA Statue/ images

 Buddhist devotees to express our reverence and gratitude to Buddha’s Dharma  teaching.

 To remind one of the qualities of Perfect Wisdom and Perfect Compassion of the Buddha.

  It’s serves to inspire us to develop these qualities as we recall the greatness of  

 the Buddha and His Teachings.

OFFERING

To make offering to Buddha is not because Buddha needs them or to give bribery or to please or exchange a favor from Buddha.

When you give something to Buddha, you ask for “return”. We are not doing business with Buddha.

We would like

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Seeds of life

Seeds of life

8 Things I Learned From the Bhagavad Gita

By YOGANONYMOUS

In the battle between heart and mind, it doesn’t matter who wins:

What matters is that you are true to both for they are not really opposed but guiding you to the truth. We balance on a narrow precipice between heart and mind: following our intuitive hearts, living with no regrets, being true to ourselves and honest with others while at the same time following our rational minds, having self-discipline and living according to our values like integrity, loyalty, honor, courage and duty.

“Surrender the fruit’s of your actions.”

Find contentment with the journey you are on regardless of outcomes, even when the walls are crumbling around you and the earth is cracking beneath your feet. “Do not expect or fear anything.” Expectation and fear limit our possibilities.

Accept the dualities of life:

“Be at ease in pleasure and pain, in honor and disgrace. Do not rejoice in good fortune nor lament bad fortune. Free yourself from desire and anger.”

Imagine your most disgraceful moment and then imagine yourself at ease in it, sitting quietly while the leaves of worry float away in the breeze. Feeling sad about your losses will weigh you down. Accept your desire without coveting or needing that which you want. Jettison anger as quickly as possible for it is the poison that seeps into our hearts if we don’t let it go.

Accept the equanimity of life:

When you see all beings as equal in suffering and in joy, when you are rooted in the oneness of all beings, you cannot love or hate because it is all part of the same thing. Put in other words, love your enemy as yourself. Refuse to speak badly about those who hurt you or your enemies. Limiting your speech will limit your negative thoughts and eventually allow you to forgive in your heart and mind as well. Then you can approach your enemies with kindness and empathy.

“The wise are free of attachments and act for the well-being of the whole world.”

Free yourself from being overly attached to things. Love without needing or possessing. Hope and dream without being attached to the outcome of your dreams. Think about what you can give to the world rather than your own problems.

“Lucid, with mind unshaken, remain within what is real.”

Speak the truth with kindness. If the truth will cause pain, evaluate your intentions to determine if it really needs to be said. Lucidity may bring to the surface many difficult choices. You cannot pretend when you are living an authentic life.

Live in accordance with your essential nature:

“It is better to do your own duty badly, than to perfectly do another’s. Even the wise man acts in accordance with his inner nature. All beings follow their nature. What good can repression do?”

To determine our dharma, or essential nature, we must look within. We will know our life’s purpose when we know our essential nature, when we are true to ourselves and pursue what we love.

“The wise man does not unsettle the minds of the ignorant; quietly acting in the spirit of yoga, he inspires them to do the same.”

Do not revel in your own voice. Quietly lead by example and inspire others to do the same. Learn to love solitude and silence.

Make Memories Not Regrets

40 Ways to Live Life Without Regrets

By Jenny Nichols

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“The saddest summary of life contains three descriptions: could have, might have, and should have.” ~ Unknown

We all have something stored in our memory banks of the past that we wish we could have done differently, or something we wish we didn’t do.

As we get older we learn and grow. But that doesn’t mean we have to regret what we did before we learned how to do things differently. If we didn’t go through those experiences we might not have grown into the strong and knowledgeable people we are today.

So what I’m proposing is that we get rid of the negative thoughts—the could have’s, might have’s, and should have’s—and start living a life that won’t make us feel regretful. Not even at an older, wiser age.

Here is a list of 40 things you can do to practice living life with no regrets:

1. Realize that it’s okay to make mistakes. Just make sure to learn from your past mistakes, forgive yourself and move on.

2. Make your health and wellness a top priority and always take care of yourself so you’re ready to take care of others.

3. Follow your own path—not one that others want you to follow.

4. Find the humor in life and laugh like there is no tomorrow.

5. Relax and move with the flow of life by being unafraid of change.

6. Be adventurous by trying new things and taking more risks.

7. Have more intellectual curiosity and embrace creativity.

8. Try to find happiness with as many different people as you can.

9. Think for yourself instead of letting other people’s opinions influence you too much.

10. Try not to judge people before you get to know them.

11. Be thankful for what you have now instead of thinking about what you don’t have.

12. Wish well upon everyone equally and try to admire without envy.

13. Share your happiness with others instead of hoarding it all for yourself.

14. Don’t try to change someone—love who they are now.

15. Enjoy the journey, not just the destination.

16. Know that happiness is bigger than any bank account.

17. Control negative thoughts so that they don’t contribute to the outcome of your life.

18. Use your energy wisely because spending energy complaining, worrying or being impatient is just wasted energy.

19. Be bold. Find the courage to change things that should be changed and accept that there are some things that cannot be changed.

20.Love your work. If you don’t currently love what you do, figure out what you would love, and take the first step toward that life.

21. Turn your discontent into a mystery and enjoy trying to solve it.

22. Face problems from different angles in order to find solutions.

23. Gain independence by realizing that on this earth we are all dependent upon each other.

24. Change your perspective by taking on a wider view of things.

25. Don’t waste time trying to bring disagreeable people around to liking you.

26. Become the person you would like to spend the rest of your life with.

27. Be honest with yourself and others by saying what you mean and meaning what you say.

28. Treat people with respect and compassion.

29. Live in the now by loving the present and being aware of your thoughts and actions. Think happy thoughts and speak powerful words.

30. Try not to put things off until later.

31. Never hold grudges.

32. Face your fears head on and try to do the things that you think you cannot do.

33. Spend time with people who make you happy while also not depending on other people for your own happiness.

34. Stand up for yourself and others and don’t let anyone or anything hold you back.

35. Be yourself and love who you are now.

36. Be a participant in life rather than an observer.

37. Do the things that you love to do as much as you can.

38. Write out a list of goals and achieve them by doing them step by step. Don’t give up when things get difficult.

39. Do something every day that makes you feel proud of yourself—commit random acts of kindness whenever you get the chance.

40. And always keep on moving forward.

I know it seems like a rather large list of things to take on, but you can accomplish a lot on this list by doing just one thing. For example, right now as I’m typing this I’m putting into practice at least 18 things.

Put these things into practice and see where life takes you, without regrets. And please comment below. I’d love to read your thoughts on this.

Before you go—one of the things I don’t want to regret is not helping friends when they need me. I’ve recently set up a blog to help a friend of mine who is in a tough situation. I’ve learned that if you are in a position to help someone you should try, and so that’s what I’m doing. Check it out if you want to help, too.